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Summary Table. Rotavirus Vaccine for the Prevention of Rotavirus Gas Among Children Recommendations of the Advisory Committee on
Immunization Practices (ACIP)
Summary Table. Recommendations and Quality of Evidence
Rotavirus Vaccine Recommendations
Advisory Committee on Immunization Practices, 1999
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Summary Table. Recommendations and Quality of Evidence
Rotavirus Vaccine Recommendations Advisory Committee on Immunization Practices, 1999
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Level of Strength of
Recommendations Evidence* Evidence+
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Provide routine vaccination at 2,4,and 6 months of age. I A
Administer to breastfed infants. I A
Administer with DTP (or DTaP),Hib vaccine,OPV,IPV,and hepatitis B vaccine. I A
Administer to infants with mild illnesses. I B
Not recommended for
Infants with known or suspected immunodeficiency III C
Infants with hypersensitivity to vaccine components III B
Infants with acute gastrointestinal disease III C
Infants with moderate to severe febrile illness III C
Precautions and special situations
Premature infants (<37 weeks gestational age) III C
Infants living in households with immunocompromised persons III C
Timing of administration of antibody-containing blood products and rotavirus vaccination III C
Infants with preexisting chronic gastrointestinal illnesses III C
Vaccine that is regurgitated III C
Late or incomplete immunization III C
Children hospitalized after vaccination III C
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* Level of Evidence
I Evidence from randomized, controlled trials
II Evidence from other epidemiologic studies
III Opinions of authorities
+ Strength of Evidence
A Good evidence to support recommendation
B Fair evidence to support recommendation
C Insufficient evidence
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