Original site: www.cdc.gov/mmwr/preview/mmwrhtml/00015468.htm RestoredCDC.org is an independent project and is not affiliated with, endorsed by, or associated with the Centers for Disease Control and Prevention (CDC) or any government entity. The CDC provides information free of change at CDC.gov. Note the following: 1) Due to archival on January 6, 2025, no information on recent outbreaks is available. 2) Videos have not been restored. 3) Use of this site implies acceptance of this disclaimer.
Notice to Readers
Unavailability of Streptomycin and Para-Aminosalicylic Acid
in the United States
Streptomycin (SM) and para-aminosalicylic acid (PAS),
antimicrobial agents used to treat tuberculosis (TB), are currently
unavailable in the United States. Because of problems in the supply
of bulk SM, which is produced outside the United States, the U.S.
manufacturer has ceased production of the finished product. The
U.S. manufacturer of PAS has voluntarily discontinued production on
a temporary basis. Although CDC and the Food and Drug
Administration are attempting to reestablish production of these
drugs, health-care providers should be prepared for an interruption
in their supply. For guidance in selecting appropriate alternatives
to SM and PAS for the treatment of TB, health-care providers should
contact their state or local TB control program.
Disclaimer
All MMWR HTML documents published before January 1993 are electronic conversions from ASCII text into HTML. This conversion may have resulted in character translation or format errors in the HTML version. Users should not rely on this HTML document, but are referred to the original MMWR paper copy for the official text, figures, and tables. An original paper copy of this issue can be obtained from the Superintendent of Documents, U.S. Government Printing Office (GPO), Washington, DC 20402-9371; telephone: (202) 512-1800. Contact GPO for current prices.
**Questions or messages regarding errors in formatting should be addressed to mmwrq@cdc.gov.
