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          The National Institute for Occupational Safety and Health (NIOSH)
         1. Registry of Toxic Effects of Chemical Substances (RTECS)
      Hydrobromic acid
            Related Pages
                RTECS #
                  MW3850000
                CAS #
                  10035-10-6
                  See: NMAM or OSHA Methods
                Updated
                  October 2015
                Molecular Weight
                  80.92
                Molecular Formula
                  BrH
                Synonyms
                  Acide bromhydrique (French)
                  Acido bromidrico (Italian)
                  Anhydrous hydrobromic acid
                  Bromowodor (Polish)
                  Bromwasserstoff (German)
                  Broomwaterstof (Dutch)
                  Hydrogen bromide
                  Hydrogen bromide (ACGIH:OSHA)
        Acute Toxicity Data and References
          Route/Organism        Dose                                                  Effect                                                                                                       Reference            
          In Vitro/Human, skin  Inhibitor Concentration Low: 48 pph/3M                In Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.  TIVIEQ 28,616,2014   
          inhalation/mouse      lethal concentration (50 percent kill): 814 ppm/1H                                                                                                                 ENTOX* -,537,2005    
          inhalation/rat        lowest published toxic concentration: 10 mg/m3/4H     Lung, Thorax, or Respiration: Other changes                                                                  TPKVAL 14,73,1975    
                                                                                      Olfaction: Change in sensation of smell                                                                                           
          inhalation/rat        lowest published toxic concentration: 26 mg/m3                                                                                                                     VCVN5* -,393,1989    
                                                                                      Lung, Thorax, or Respiration: Dyspnea                                                                                             
          inhalation/rat        lethal concentration (50 percent kill): 3000 ppm/30M                                                                                                               ENTOX* -,639,2005    
          inhalation/rat        lethal concentration (50 percent kill): 2858 ppm/1H                                                                                                                ENTOX* -,537,2005    
          intraperitoneal/rat   lethal dose (50 percent kill): 76 mg/kg                                                                                                                            GISAAA 41(1),105,1976
          Reviews
            Organization                                                       Standard                                           Reference          
            American Conference of Governmental Industrial Hygienists (ACGIH)  Threshold Limit Value-ceiling concentration 2 ppm  DTLVS* TLV/BEI,2013
            TOXICOLOGY REVIEW                                                                                                     ENTOX* -,639,2005  
            TOXICOLOGY REVIEW                                                                                                     ENTOX* -,537,2005  
            Standards and Regulations
              Organization                                                                                           Standard                                                                                 Reference               
              Mine Safety and Health Administration (MSHA) STANDARD-air                                              time-weighted average 3 ppm (10 mg/m3)                                                   DTLVS* 3,128,1971       
              Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;                                                                                                                                   
              Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV                                                                                                                                                       
              Occupational Exposure Limit-AUSTRALIA                                                                  ceiling concentration 3 ppm (9.9 mg/m3), JUL2008                                                                 
              Occupational Exposure Limit-AUSTRIA                                                                    MAK-TMW 2 ppm (6.7 mg/m3);KZW 2 ppm (6.7 mg/m3), 2007                                                            
              Occupational Exposure Limit-BELGIUM                                                                    short term exposure limit 2 ppm (6.7 mg/m3), MAR2002                                                             
              Occupational Exposure Limit-DENMARK                                                                    ceiling concentration 2 ppm (6.7 mg/m3), MAY2011                                                                 
              Occupational Exposure Limit-EC                                                                         short term exposure limit 6.7 mg/m3 (2 ppm), JUN2000                                                             
              Occupational Exposure Limit-FINLAND                                                                    short term exposure limit 2 ppm (6.7 mg/m3), NOV2011                                                             
              Occupational Exposure Limit-FRANCE                                                                     VLE 2 ppm (6.7 mg/m3), FEB2006                                                                                   
              Occupational Exposure Limit-GERMANY                                                                    MAK 2 ppm (6.7 mg/m3), 2011                                                                                      
              Occupational Exposure Limit-HUNGARY                                                                    short term exposure limit 6.7 mg/m3, SEP2000                                                                     
              Occupational Exposure Limit-ICELAND                                                                    short term exposure limit 2 ppm (6.7 mg/m3), NOV2011                                                             
              Occupational Exposure Limit-KOREA                                                                      ceiling concentration 3 ppm (10 mg/m3), 2006                                                                     
              Occupational Exposure Limit-MEXICO                                                                     peak 3 ppm (10 mg/m3), 2004                                                                                      
              Occupational Exposure Limit-NEW ZEALAND                                                                ceiling concentration 3 ppm (9.9 mg/m3), JAN2002                                                                 
              Occupational Exposure Limit-NORWAY                                                                     time-weighted average 3 ppm (10 mg/m3), JAN1999                                                                  
              Occupational Exposure Limit-PERU                                                                       short term exposure limit 3 ppm (10 mg/m3), JUL2005                                                              
              Occupational Exposure Limit-POLAND                                                                     MAC(time-weighted average) 7 mg/m3, MAC(short term exposure limit) 21 mg/m3, JAN1999                             
              Occupational Exposure Limit-RUSSIA                                                                     short term exposure limit 2 mg/m3, JUN2003                                                                       
              Occupational Exposure Limit-SWEDEN                                                                     time-weighted average 1 ppm (3.5 mg/m3), ceiling concentration 2 ppm (7 mg/m3), JUN2005                          
              Occupational Exposure Limit-SWITZERLAND                                                                ceiling concentration 2 ppm (6.7 mg/m3), JAN2011                                                                 
              Occupational Exposure Limit-THE PHILIPPINES                                                            time-weighted average 3 ppm (10 mg/m3), JAN1993                                                                  
              Occupational Exposure Limit-TURKEY                                                                     time-weighted average 5 ppm (17 mg/m3), JAN1993                                                                  
              Occupational Exposure Limit-UNITED KINGDOM                                                             short term exposure limit 3 ppm (10 mg/m3), OCT2007                                                              
              Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)         8H time-weighted average 3 ppm (10 mg/m3)                                                CFRGBR 29,1926.55,1994  
              Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)  8H time-weighted average 3 ppm (10 mg/m3)                                                CFRGBR 41,50-204.50,1994
              Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)     8H time-weighted average 3 ppm (10 mg/m3)                                                CFRGBR 29,1910.1000,1994
              Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)            8H time-weighted average 3 ppm (10 mg/m3)                                                CFRGBR 29,1915.1000,1993
              NIOSH Documentation and Surveillance
                Organization                                                                                                      Standard                                                                                                                                                                                       Reference               
                National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO HYDROGEN BROMIDE-air  ceiling concentration 3 ppm                                                                                                                                                                    NIOSH* DHHS #92-100,1992
                National Occupational Exposure Survey 1983                                                                        Hazard Code 38575; Number of Industries 23; Total Number of Facilities 1103; Number of Occupations 26; Total Number of Employees Exposed 20571; Total Number of Female Employees Exposed 5398                          
                National Occupational Hazard Survey 1974                                                                          Hazard Code 38575; Number of Industries 13; Total Number of Facilities 510; Number of Occupations 12; Total Number of Employees Exposed 2643                                                                           
                Status in Federal Agencies
                  Organization                                               Reference
                  EPA TSCA Section 8(b) CHEMICAL INVENTORY                            
                  EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001           
                  NIOSH Analytical Method, 1994: Acids, inorganic, 7903               
                Page last reviewed: November 16, 2018
                  Content source: National Institute for Occupational Safety and Health
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