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        The National Institute for Occupational Safety and Health (NIOSH)
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          The National Institute for Occupational Safety and Health (NIOSH)
         1. NIOSH Pocket Guide to Chemical Hazards
      Halothane
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        Halothane
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                Synonyms & Trade Names
                  1-Bromo-1-chloro-2,2,2-trifluoroethane, 2-Bromo-2-chloro-1,1,1-trifluoroethane, 1,1,1-Trifluoro-2-bromo-2-chloroethane, 2,2,2-Trifluoro-1-bromo-1-chloroethane
                CAS No.
                  151-67-7
                RTECS No.
                  KH6550000
                DOT ID & Guide
                Formula
                  CF₃CHBrCl
                Conversion
                  1 ppm = 8.07 mg/m3
                IDLH
                  N.D.
                  See: IDLH INDEX
                Exposure Limits
                  NIOSH REL
                  C 2 ppm (16.2 mg/m3) [60-minute] [*Note: REL for exposure to waste anesthetic gas.]
                  OSHA PEL
                  none
                Measurement Methods
                  OSHA 29
                  See: NMAM or OSHA Methods
                Physical Description
                  Clear, colorless liquid with a sweetish, pleasant odor. [inhalation anesthetic]
                Molecular Weight
                  197.4
                Boiling Point
                  122°F
                Freezing Point
                  -180°F
                Solubility
                  0.3%
                Vapor Pressure
                  243 mmHg
                Ionization Potential
                  ?
                Specific Gravity
                  1.87
                Flash Point
                  NA
                Upper Explosive Limit
                  NA
                Lower Explosive Limit
                  NA
                  Noncombustible Liquid
                Incompatibilities & Reactivities
                  May attack rubber & some plastics; sensitive to light. [Note: Light causes decomposition. May be stabilized with 0.01% thymol.]
                Exposure Routes
                  inhalation, skin absorption, ingestion, skin and/or eye contact
                Symptoms
                  irritation eyes, skin, respiratory system; confusion, drowsiness, dizziness, nausea, analgesia, anesthesia; cardiac arrhythmias; liver, kidney damage; decreased audio-visual performance; In Animals: reproductive effects
                Target Organs
                  Eyes, skin, respiratory system, cardiovascular system, central nervous system, liver, kidneys, reproductive system
                Personal Protection/Sanitation
                (See protection codes)
                Skin:Prevent skin contact
                Eyes:Prevent eye contact
                Wash skin:When contaminated
                Remove:When wet or contaminated
                Change:No recommendation
                Provide:Eyewash
                First Aid
                (See procedures)
                Eye:Irrigate immediately
                Skin:Soap wash promptly
                Breathing:Respiratory support
                Swallow:Medical attention immediately
                Respirator Recommendations
                Not available.
                Important additional information about respirator selection
                See also
                INTRODUCTION ICSC CARD: 0277
      Page last reviewed: October 30, 2019
        Content source: National Institute for Occupational Safety and Health
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      NIOSH Pocket Guide to Chemical Hazards
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      * CAS Numbers
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          + A – NIOSH Potential Occupational Carcinogens
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          + C – Supplementary Exposure Limits
          + D – Substances with No Established RELs
          + E – OSHA Respirator Requirements for Selected Chemicals
          + F – Miscellaneous Notes
          + G – 1989 Air Contaminants Update Project: Exposure Limits NOT in Effect
          + Type C & CE – Definitions for Type C and Type CE Respirators
          + Personal Protection and Sanitation Codes
          + First Aid Procedures
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