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Original site: www.cdc.gov/nchs/hus/sources-definitions/statistical-significance.htm | RestoredCDC.org is an independent project, not affiliated with CDC or any federal entity. Visit CDC.gov for free official information. Due to archival on January 6, 2025, recent outbreak data is unavailable. Videos are not restored. Access data.restoredcdc.org for restored data. Use of this site implies acceptance of this disclaimer.[More]About Us Report Bug Compare ContentSkip directly to site content Skip directly to searchEspañol | Other LanguagesHere's how you knowAn official website of the United States government Here's how you knowNational Center for Health StatisticsNational Center for Health StatisticsCenters for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People National Center for Health StatisticsSearchSearch Menu Navigation Menu× Search NCHSSearch NCHS All CDCSubmitNational Center for Health Statistics* About Health United States+ BACKAbout Health United States+ Acknowledgments+ National Center for Health Statistics Home* Annual Report+ BACKAnnual Report+ Previous Reports+ National Center for Health Statistics Home* Topics* Data Finder* Sources and Definitions+ BACKSources and Definitions+ Statistical significance+ National Center for Health Statistics Home* Resource Library+ BACKResource Library+ Webinars+ Infographics+ National Center for Health Statistics Home* National Center for Health Statistics HomeNational Center for Health StatisticsNational Center for Health Statistics HomeStatistical significanceStatistical significanceWhen trends are analyzed in Health, United States, terms such as “stable,” “no clear trend,” and “did not change significantly” indicate that the slope of the trend line was not significantly different from zero. Terms such as “increase” and “decrease” indicate that a significant trend was found.In addition to trend testing, comparisons are often made between estimates at two time points or for two populations. For data sources with standard errors, the difference between two estimates was assessed for statistical significance using z tests at the 0.05 alpha level. For data sources with no standard errors, relative differences were assessed using the methods recommended by the data source. The terms “higher” or “highest” and “lower” or “lowest” indicate that the estimates were significantly different, while the terms “similar,” “no difference,” and “no change” indicate that the estimates were not significantly different. Lack of comment does not necessarily indicate that trends or differences were tested and found to be not significant. Data sets include point estimates and standard errors, when available, for data users who would like to perform additional statistical tests.Statistical significance of differences or trends is partly a function of sample size (that is, the larger the sample, the smaller the change that can be detected), and statistical significance does not always indicate public health significance. Moreover, a small sample size may result in statistically nonsignificant results despite the existence of potentially meaningful differences. For more information, see Wasserstein RL, Lazar NA. The ASA’s statement on p-values: Context, process, and purpose. Am Stat 70(2):129–33. 2016. (Also see Sources and Definitions, Joinpoint trend analysis software; Statistical testing.)Last Reviewed: July 30, 2024Source: CDC/National Center for Health Statistics/Division of Analysis and Epidemiology* Syndicatehome Health, United States* About Health United States plus icon+ Acknowledgments* Annual Report plus icon+ Previous Reports* Topics* Data Finder* Sources and Definitions+ Statistical significance* Resource Library plus icon+ Webinars+ Infographics* About CDC* Contact Us* 800-232-4636Facebook Twitter Instagram LinkedIn Youtube Pinterest SnapchatFacebook Twitter Instagram LinkedIn Youtube Pinterest Snapchat RSS* CONTACT CDCContact UsCall 800-232-4636Email Us* ABOUT CDC+ About CDC+ Jobs+ Funding* POLICIES+ Accessibility+ External Links+ Privacy+ Policies+ Web Policies+ No Fear Act+ FOIA+ OIG+ No Fear Act+ Nondiscrimination+ Vulnerability Disclosure Policy+ CDC Archive+ Public Health Publications+ HHS.gov+ USA.gov* CONNECT WITH US+ Youtube+ Snapchat* LANGUAGES+ Español+ 繁體中文+ Tiếng Việt+ 한국어+ Tagalog+ Русский+ العربية+ Kreyòl Ayisyen+ Français+ Polski+ Português+ Italiano+ Deutsch+ 日本語+ فارسی+ English* U.S. Department of Health & Human Services* Accessibility* External Links* Privacy* Policies* Web Policies* FOIA* OIG* No Fear Act* FOIA* Nondiscrimination* OIG* Vulnerability Disclosure Policy* CDC Archive* Public Health Publications* HHS.gov* USA.govContent Credential×This image was edited or created using GenAI (generative artificial intelligence).Our experts review all images in an effort to ensure accuracy and quality before use.Learn more about CDC's usage of GenAI.
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