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o Figure 1.1 – Number of Cases & Estimated Infections
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o Figure 2.1 – Acute – Number of Cases
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o Table 2.1 – Acute – Number & Rates of Cases
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o Figure 3.1 – Acute – Number of Cases
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o Table 3.1 – Acute – Number & Rates of Cases
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o Figure 1.1 – Number of Cases & Estimated Infections
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o Table 2.1 – Acute – Numbers & Rates of Cases
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o Figure 3.1 – Acute – Number of Cases & Estimated Infections
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o Table 3.1 – Acute – Number & Rates of Cases
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o Figure 1.1 – Number of Cases & Estimated Infections
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o Figure 1.3 – Map of Case Rates
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o Figure 1.6 – Case Rates by Race & Ethnicity
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o Figure 2.1 – Acute – Number of Cases & Estimated Infections
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o Table 2.1 – Acute – Number & Rates of Cases
o Table 2.2 – Acute – Cases & Rates by Demographics
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o Figure 3.1 – Acute – Number of Cases & Estimated Infections
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o Figure 3.4 – Acute – Case Rates by Age Group
o Figure 3.5 – Acute – Case Rates by Sex
o Figure 3.6 – Acute – Case Rates by Race & Ethnicity
o Figure 3.7 – Acute – Risk & Exposure Data
o Figure 3.8 – Chronic – Case Rates by Sex & Age
o Figure 3.9 – Map of Death Rates
o Table 3.1 – Acute – Number & Rates of Cases
o Table 3.2 – Acute – Cases & Rates by Demographics
o Table 3.3 – Acute – Risk & Exposure Data
o Table 3.4 – Perinatal – Cases by Jurisdiction
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o Figure 5.1 – Hepatitis B & C Rates 18-40 years
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o Table 2.1
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o Table 3.1
o Table 3.2
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Hepatitis C Surveillance 2021
Hepatitis C
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What Is Hepatitis C
Hepatitis C is a liver disease caused by the hepatitis C virus (HCV). HCV is a bloodborne virus. Transmission can happen through sharing needles, syringes, or other drug-injection equipment; from the gestational parent to baby during pregnancy or at birth; or rarely through sexual contact.
On this page
* What is Hepatitis C?
* Hepatitis C in 2021
* Acute Hepatitis C
* Chronic Hepatitis C
* Hepatitis C Figures & Tables
Today, in the United States, the majority of persons become infected with HCV by sharing needles or other equipment used to inject drugs. For certain persons, hepatitis C is a short-term illness, but for more than half of persons who become infected with HCV, it becomes a long-term, chronic infection.
Like chronic hepatitis B, chronic hepatitis C is a serious disease that can result in cirrhosis, liver cancer, and death. Persons might not be aware of their infection because they do not have symptoms.
Since 2013, highly effective, well-tolerated curative treatments have been available for hepatitis C, but no vaccine for preventing hepatitis C is yet available.
The best way to prevent hepatitis C is by avoiding behaviors that can spread the disease, especially injecting drugs with non-sterile injection equipment.
Hepatitis C in 2021
Acute Hepatitis C
5,023
T here were 5,023 new cases of acute hepatitis C reported during 202 1
69,800
There were 69,800 estimated acute hepatitis C virus infections during 202 1
Chronic Hepatitis C
107, 540
T here were 107, 540 cases of newly reported chronic hepatitis C during 202 1
39.8
There were 39.8 newly reported cases of chronic hepatitis C per 100,000 people
Acute Hepatitis C in 2021
The number of reported cases of acute hepatitis C has doubled since 201 4 (12 9 % increase), and during 202 1 increased 5% from 20 20 .
There was a change to how public health defines a case of acute hepatitis C in 2020. This more sensitive and accurate definition helped capture cases that the less sensitive definition might have missed. This increase in cases detected due to the case definition change likely made up for any decreases that may have occurred due to the impact of the COVID-19 pandemic in 2020 and 2021.
In 2020, CDC published universal adult and pregnancy screening guidelines. It is important that health care professionals , public health officials, and organizations involved in the development, implementation, delivery, and evaluation of clinical and preventive services follow and use these recommendations.
Fast Facts About Acute Hepatitis C in 2021
2x
The number of acute hepatitis C case s has doubled since 201 4 , a 12 9 % increase
Non-Hispanic American Indian/Alaska Native
Rates of acute hepatitis C are highest among non-Hispanic American Indian / Alaska Native persons
20– 39
Persons aged 20–39 years had the highest incidence of acute hepatitis C
57%
57% of cases with risk information reported injection drug use
During 202 1 , rates of acute hepatitis C were highest among males, persons age d 20 – 39 years , non-Hispanic American Indian/Alaska Native (AI/AN) persons , and those living in the E astern and S outheastern states . Among cases with risk information reported, the most common was injection drug use .
Chronic Hepatitis C in 2021
During 2021, 43 states reported a total of 107,300 newly identified chronic hepatitis C cases in 2021, corresponding to 39.8 chronic hepatitis C cases per 100,000 people.
Hepatitis C-associated deaths during 2021 decreased 8% (3.18 deaths per 100,000 people), compared to 2020 (3.45 deaths per 100,000 people).
The age-adjusted death rate for hepatitis C during 2021 decreased 23% from 2017 (4.13 deaths per 100,000 people).
The death rates were higher among non-Hispanic AI/AN and non-Hispanic Black persons (3.4 times and 1.7 times, respectively) than among non-Hispanic White persons.
Fast Facts About Chronic Hepatitis C in 2021
65%
During 202 1 , 6 5 % of newly reported chronic hepatitis C cases occurred among men
66.9
During 202 1 , the rate of newly reported chronic hepatitis C cases was highest among non-Hispanic AI/AN persons at 66. 9 cases per 100,000 p eople
Chronic Hepatitis C affects multiple generations with infections highest among two age groups: 20–39 and 55–70 years.
Hepatitis C Figures and Tables
* Figure 3.1. Number of reported cases of acute hepatitis C virus infection and estimated infections — United States, 2014–2021
* Figure 3.2. Rates of reported cases of acute hepatitis C virus infection, by state or jurisdiction — United States, 2020–2021
* Figure 3.3. Rates of reported cases of acute hepatitis C virus infection, by state or jurisdiction — United States, 2021
* Figure 3.4. Rates* of reported cases of acute hepatitis C virus infection, by age group — United States, 2006–2021
* Figure 3.5. Rates of reported cases of acute hepatitis C virus infection, by sex — United States, 2006–2021
* Figure 3.6. Rates of reported cases of acute hepatitis C virus infection, by race/ethnicity — United States, 2006–2021
* Figure 3.7. Availability of information on risk behaviors or exposures associated with reported cases of acute hepatitis C virus infection — United States, 2021
* Figure 3.8. Number of newly reported chronic hepatitis C virus infection cases by sex and age — United States, 2021
* Figure 3.9. Rates of death with hepatitis C virus infection listed as a cause of death among residents, by state or jurisdiction — United States, 2021
* Table 3.1. Numbers and rates of reported cases† of acute hepatitis C virus infection, by state or jurisdiction — United States, 2017–2021
* Table 3.2. Numbers and rates of reported cases† of acute hepatitis C virus infection, by demographic characteristics — United States, 2017–2021
* Table 3.3. Reported risk behaviors or exposures among reported cases of acute hepatitis C virus infection — United States, 2021
* Table 3.4. Number of newly reported cases of perinatal hepatitis C virus infection, by state or jurisdiction — United States, 2021
* Table 3.5. Number and rate of newly reported cases of chronic hepatitis C virus infection, by state or jurisdiction — United States, 2021
* Table 3.6. Number and rate of newly reported cases of chronic hepatitis C virus infection, by demographic characteristics — United States, 2021
* Table 3.7. Numbers and rates of deaths with hepatitis C listed as a cause of death among residents, by state or jurisdiction — United States, 2017–2021
* Table 3.8. Numbers and rates of deaths with hepatitis C virus infection listed as a cause of death among residents, by demographic characteristics — United States, 2017–2021
Last Reviewed: August 7, 2023
Source: Division of Viral Hepatitis, National Center for HIV, Viral Hepatitis, STD, and TB Prevention
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o Background
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o Figure 1.1 – Number of Cases & Estimated Infections
o Figure 1.2 – Case Rates by Jurisdiction
o Figure 1.3 – Map of Case Rates
o Figure 1.4 – Case Rates by Age Group
o Figure 1.5 – Case Rates by Sex
o Figure 1.6 – Case Rates by Race & Ethnicity
o Figure 1.7 – Infection Risk Behaviors
o Table 1.1 – Number & Rates of Cases by Jurisdiction
o Table 1.2 – Cases & Rates by Demographics
o Table 1.3 – Cases by Risk Behaviors
o Table 1.4 – Death Rates by Demographics
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o Figure 2.1 – Acute – Number of Cases
o Figure 2.2 – Acute – Case Rates by Jurisdiction
o Figure 2.3 – Acute – Map of Case Rates
o Figure 2.4 – Acute – Case Rates by Age Group
o Figure 2.5 – Acute – Case Rates by Sex
o Figure 2.6 – Acute – Case Rates by Race & Ethnicity
o Figure 2.7 – Acute – Infection Risk
o Figure 2.8 – Map of Death Rates
o Table 2.1 – Acute – Number & Rates of Cases
o Table 2.2 – Acute – Cases & Rates by Demographics
o Table 2.3 – Acute – Cases by Risk Behaviors
o Table 2.4 – Perinatal – Cases by Jurisdiction
o Table 2.5 – Chronic – Case Rates by Jurisdiction
o Table 2.6 – Chronic – Case Rates by Demographics
o Table 2.7 – Death Rates by Jurisdiction
o Table 2.8 – Death Rates by Demographics
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o Figure 3.1 – Acute – Number of Cases
o Figure 3.2 – Acute – Case Rates by Jurisdiction
o Figure 3.3 – Acute – Map of Case Rates
o Figure 3.4 – Acute – Case Rates by Age Group
o Figure 3.5 – Acute – Case Rates by Sex
o Figure 3.6 – Acute – Case Rates by Race & Ethnicity
o Figure 3.7 – Acute – Infection Risk Behaviors
o Figure 3.8 – Chronic – Case Rates by Sex & Age
o Figure 3.9 – Map of Death Rates
o Table 3.1 – Acute – Number & Rates of Cases
o Table 3.2 – Acute – Cases & Rates by Demographics
o Table 3.3 – Acute – Infection Risk Behaviors
o Table 3.4 – Perinatal – Cases by Jurisdiction
o Table 3.5 – Chronic – Case Rates by Jurisdiction
o Table 3.6 – Chronic – Case Rates by Demographics
o Table 3.7 – Death Rates by Jurisdiction
o Table 3.8 – Death Rates by Demographics
+ Perinatal Hepatitis B Prevention Program plus icon
o Figure 4.1 – Outcomes by Birth Cohort Year
o Table 4.1 – Outcomes by Jurisdiction
+ Appendix plus icon
o Figure 5.1 – Reported Acute Hepatitis B & C Cases
o Table 5.1 – Acute Viral Hepatitis Cases
o Table 5.2 – Acute & Chronic Hepatitis C Cases
o Table 5.3 – Numbers & Rates of Reported Acute Hepatitis B & C
o Figures & Tables – 2022 Viral Hepatitis Surveillance Report
* 2021 Surveillance plus icon
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o Background
o National Profile of Viral Hepatitis
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o Figure 1.1 – Number of Cases & Estimated Infections
o Figure 1.2 – Case Rates by Jurisdiction
o Figure 1.3 – Map of Case Rates
o Figure 1.4 – Case Rates by Age Group
o Figure 1.5 – Case Rates by Sex
o Figure 1.6 – Case Rates by Race/Ethnicity
o Figure 1.7 – Risk & Exposure Data
o Table 1.1 – Number & Rates of Cases by Jurisdiction
o Table 1.2 – Cases & Rates by Demographics
o Table 1.3 – Risk & Exposure Data
o Table 1.4 – Death Rates by Demographics
+ Hepatitis B plus icon
o Figure 2.1 – Acute – Number of Cases & Estimated Infections
o Figure 2.2 – Acute – Case Rates by Jurisdiction
o Figure 2.3 – Acute – Map of Case Rates
o Figure 2.4 – Acute – Case Rates by Age Group
o Figure 2.5 – Acute – Case Rates by Sex
o Figure 2.6 – Acute – Case Rates by Race/Ethnicity
o Figure 2.7 – Acute – Risk & Exposure
o Figure 2.8 – Map of Death Rates
o Table 2.1 – Acute – Numbers & Rates of Cases
o Table 2.2 – Acute – Cases & Rates by Demographics
o Table 2.3 – Acute – Risk & Exposure Data
o Table 2.4 – Perinatal – Cases by Jurisdiction
o Table 2.5 – Chronic – Case Rates by Jurisdiction
o Table 2.6 – Chronic – Case Rates by Demographics
o Table 2.7 – Death Rates by Jurisdiction
o Table 2.8 – Death Rates by Demographics
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o Figure 3.1 – Acute – Number of Cases & Estimated Infections
o Figure 3.2 – Acute – Case Rates by Jurisdiction
o Figure 3.3 – Acute – Map of Case Rates
o Figure 3.4 – Acute – Case Rates by Age Group
o Figure 3.5 – Acute – Case Rates by Sex
o Figure 3.6 – Acute – Case Rates by Race/Ethnicity
o Figure 3.7 – Acute – Risk & Exposure Data
o Figure 3.8 – Chronic – Case Rates by Sex & Age
o Figure 3.9 – Map of Death Rates
o Table 3.1 – Acute – Number & Rates of Cases
o Table 3.2 – Acute – Cases & Rates by Demographics
o Table 3.3 – Acute – Risk & Exposure Data
o Table 3.4 – Perinatal – Cases by Jurisdiction
o Table 3.5 – Chronic – Case Rates by Jurisdiction
o Table 3.6 – Chronic – Case Rates by Demographics
o Table 3.7 – Death Rates by Jurisdiction
o Table 3.8 – Death Rates by Demographics
+ Perinatal Hepatitis B Prevention Program plus icon
o Figure 4.1 – Outcomes by Birth Cohort Year
o Table 4.1 – Outcomes by Jurisdiction
+ Appendix plus icon
o Figure 5.1 – Number of Cases & Estimated Infections for 18–40 Years
o Table 5.1 – Reported Cases & Estimated Infections – 95% CI
o Table 5.2 – Acute & Chronic Hepatitis C Cases Confirmed and Probable
o Table 5.3 – Hepatitis B & C for 18–40 Years
o Tables & Figures – 2021 Viral Hepatitis Surveillance Report
* 2020 Surveillance plus icon
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o Background
o National Profile of Viral Hepatitis
o Technical Notes
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o Figure 1.1 – Number of Cases & Estimated Infections
o Figure 1.2 – Case Rates by Jurisdiction
o Figure 1.3 – Map of Case Rates
o Figure 1.4 – Case Rates by Age Group
o Figure 1.5 – Case Rates by Sex
o Figure 1.6 – Case Rates by Race & Ethnicity
o Figure 1.7 – Risk & Exposure Data
o Table 1.1 – Number & Rates of Cases by Jurisdiction
o Table 1.2 – Cases & Rates by Demographics
o Table 1.3 – Risk & Exposure Data
o Table 1.4 – Death Rates by Demographics
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o Figure 2.1 – Acute – Number of Cases & Estimated Infections
o Figure 2.2 – Acute – Case Rates by Jurisdiction
o Figure 2.3 – Acute – Map of Case Rates
o Figure 2.4 – Acute – Case Rates by Age Group
o Figure 2.5 – Acute – Case Rates by Sex
o Figure 2.6 – Acute – Case Rates by Race & Ethnicity
o Figure 2.7 – Acute – Risk & Exposure
o Figure 2.8 – Map of Death Rates
o Table 2.1 – Acute – Number & Rates of Cases
o Table 2.2 – Acute – Cases & Rates by Demographics
o Table 2.3 – Acute – Risk & Exposure Data
o Table 2.4 – Perinatal – Cases by Jurisdiction
o Table 2.5 – Chronic – Case Rates by Jurisdiction
o Table 2.6 – Chronic – Case Rates by Demographics
o Table 2.7 – Death Rates by Jurisdiction
o Table 2.8 – Death Rates by Demographics
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o Figure 3.1 – Acute – Number of Cases & Estimated Infections
o Figure 3.2 – Acute – Case Rates by Jurisdiction
o Figure 3.3 – Acute – Map of Case Rates
o Figure 3.4 – Acute – Case Rates by Age Group
o Figure 3.5 – Acute – Case Rates by Sex
o Figure 3.6 – Acute – Case Rates by Race & Ethnicity
o Figure 3.7 – Acute – Risk & Exposure Data
o Figure 3.8 – Chronic – Case Rates by Sex & Age
o Figure 3.9 – Map of Death Rates
o Table 3.1 – Acute – Number & Rates of Cases
o Table 3.2 – Acute – Cases & Rates by Demographics
o Table 3.3 – Acute – Risk & Exposure Data
o Table 3.4 – Perinatal – Cases by Jurisdiction
o Table 3.5 – Chronic – Case Rates by Jurisdiction
o Table 3.6 – Chronic – Case Rates by Demographics
o Table 3.7 – Death Rates by Jurisdiction
o Table 3.8 – Death Rates by Demographics
+ Perinatal Hepatitis B Prevention Program plus icon
o Figure 4.1 – Outcomes by Birth Cohort Year
o Table 4.1 – Outcomes by Jurisdiction
+ Appendix plus icon
o Figure 5.1 – Hepatitis B & C Rates 18-40 years
o Table 5.1 – Estimated infections and 95% CI
o Table 5.2 – Acute & Chronic Hepatitis C Cases Confirmed and Probable
o Table 5.3 – Hepatitis B & C Rates 18-40 years
o Tables & Figures | 2020 Viral Hepatitis Surveillance Report
* 2019 Surveillance plus icon
+ Introduction
+ Hepatitis A plus icon
o Figure 1.1
o Figure 1.2
o Figure 1.3
o Figure 1.4
o Figure 1.5
o Figure 1.6
o Figure 1.7
o Table 1.1
o Table 1.2
o Table 1.3
o Table 1.4
+ Hepatitis B plus icon
o Figure 2.1
o Figure 2.2
o Figure 2.3
o Figure 2.4
o Figure 2.5
o Figure 2.6
o Figure 2.7
o Figure 2.8
o Table 2.1
o Table 2.2
o Table 2.3
o Table 2.4
o Table 2.5
o Table 2.6
o Table 2.7
o Table 2.8
+ Hepatitis C plus icon
o Figure 3.1
o Figure 3.2
o Figure 3.3
o Figure 3.4
o Figure 3.5
o Figure 3.6
o Figure 3.7
o Figure 3.8
o Figure 3.9
o Table 3.1
o Table 3.2
o Table 3.3
o Table 3.4
o Table 3.5
o Table 3.6
o Table 3.7
o Table 3.8
+ Appendix
+ Supplemental Report
* 2018 Surveillance plus icon
+ Introduction
+ Hepatitis A
+ Hepatitis B
+ Hepatitis C
+ Appendix
* 2017 Surveillance plus icon
+ Hepatitis A Tables and Figures
+ Hepatitis B Tables and Figures
+ Hepatitis C Tables and Figures
* 2016 Surveillance plus icon
+ Commentary
+ Table 1.1 Hepatitis C Outbreaks
* 2015 Surveillance plus icon
+ Commentary
+ Table 1.1 Hepatitis C Outbreaks
* 2014 Surveillance plus icon
+ Commentary
* 2013 Surveillance plus icon
+ Commentary plus icon
o Erratum
* 2012 Surveillance plus icon
+ Commentary
* 2011 Surveillance plus icon
+ Commentary
* 2010 Surveillance plus icon
+ Commentary
* 2009 Surveillance plus icon
+ Commentary
* 2008 Surveillance plus icon
+ Commentary
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